Got this in an email about a possible drug...
Huntington's disease clinical trials news, including the first 'huntingtin lowering' trial
Welcome to HDBuzzCast, the official podcast of HDBuzz! In this inaugural episode, Dr Ed Wild and Dr Jeff Carroll introduce HDBuzzCast and talk about the five new clinical trials enrolling now or starting soon for Huntington's disease. Plus, a detailed discussion of the eagerly-awaited clinical trial of the first 'huntingtin lowering' drug to be tested in Huntington's diease. Called HTT-Rx, the drug is an antisense oligonucleotide developed by Isis Pharmaceuticals Inc. If you have questions about any aspect of HD research, send them to firstname.lastname@example.org.
What do you think?
I am so excited by this news of the HTT-Rx trial, it is what so many of us have been waiting for! I couldn't see any details about where this trial is being conducted, and whether any of the phases will be in Australia. I'll send an email to the email address above, but when I got the email from HDBuzz yesterday, I was thrilled!
I'll be sure to listen to this podcast.
Hi Chels - I personally am very excited about this. My mum has HD (diagnosed a year ago) and this means a lot to us as a family. I have a few questions though which I'm hoping you can answer. Who will this drug be ideal for? Those who have had HD for yrs or those in the early stages or both? I know the aim of this is to potentially stop symptoms or halt them completely, but will this also halt premature death of patients with HD? Is this treatment also in mind for those at risk of HD, such as myself? Is the idea for this to be administered before any symptoms arise? Sorry for all the questions, I am very curious!
They are doing preliminary testing starting in 2015. Right now they are focusing on people who have symptoms to do the trials. They do not have all the answers yet. BUT stay tuned and the article goes into more detail about the testing process and the hope of what this drug can do.